Complete Information on Angiosarcoma of the breast with Treatment and Prevention

Angiosarcomas are pernicious, and they may not develop symptoms until the disease is easily advanced.

Angiosarcoma of the breast is an uncommon, extremely hostile neoplasm of vascular origin. Angiosarcomas are aggressive and tend to recur locally, spread widely, and have a high rate of lymph node and systemic metastases. The rate of tumor-related death is high. Angiosarcomas also can originate in the liver, breast, spleen, bone, or heart. Secondary angiosarcomas usually occur in older women years following the treatment of breast cancer. They can arise in the lymphedemateous upper extremity years following radical mastectomy and irradiation. Secondary angiosarcomas can also arise in the chest wall following mastectomy and irradiation, or in the breast following breast conserving therapy. The etiology of most cases of angiosarcoma is unknown. The tumors may develop as a complication of a preexisting condition. Some angiosarcomas are associated with foreign material introduced in the body, either iatrogenically or accidentally.

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